Torsades de pointes tachycardia induced by common cold compound medication containing chlorpheniramine

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Torsades de pointes induced by antibiotics.

BACKGROUND Several frequently used antibiotics are associated with an arrhythmia called "torsades de pointes" (TdP). This potentially fatal arrhythmia is considered unpredictable. METHODS In order to investigate the prevalence of risk factors for TdP prior to initiation of antibiotic therapy, we conducted a literature search for all published reports on TdP induced by antibiotics and we asked...

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Torsades de pointes induced by concomitant use of chlorpheniramine and propranolol: An unusual presentation with no QT prolongation

Drug-induced torsades de pointes (TdP) is a rare but potentially fatal adverse effect of commonly prescribed medications including cardiac and noncardiac drugs. Importantly, many drugs have been reported to cause the characteristic Brugada syndrome-linked electrocardiography (ECG) abnormalities and/or (fatal) ventricular tachyarrhythmias. Chlorpheniramine and propranolol have the arrhythmogenic...

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ژورنال

عنوان ژورنال: European Journal of Clinical Pharmacology

سال: 2010

ISSN: 0031-6970,1432-1041

DOI: 10.1007/s00228-010-0875-5